Moses - Single-cell technologies

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Diese Modulbeschreibung gilt nicht im aktuellen Semester.

Die Modulbeschreibung gilt nur für den Zeitraum SS 2017 - WS 2017/18.

Module / Version:
#30675 / #1

Validity:
SS 2017 - WS 2017/18

Default display language:
English

Module title:
Single-cell technologies

Credits:
2

Responsible person:
Lauster, Roland

Grading:
benotet

Type of exam:
Mündliche Prüfung

Zugehörigkeit

Faculty:
Fakultät III

Institute:
Institut für Biotechnologie

Area of expertise:
33311100 FG Medizinische Biotechnologie

Prüfungsausschuss:
MSc Biotechnologie

Kontakt

Office:
TIB 4/4-2

Contact person:
Peters, Manuela

E-mail address:
roland.lauster@tu-berlin.de

Website:

http://www.medbt.tu-berlin.de

Learning Outcomes

A tissue is composed of many different cell types, each of which can have variable biological states. Rather than studying global processes, molecular characterization at the single-cell level would provide a much more complete and accurate picture of its biological function. Such an approach has been very limited though, since conventional methods typically fail to recognize this complexity as they only consider a given input material as a whole. Recent advances in single-cell technologies are currently revolutionizing many fields of biological research by making it possible to profile individual cells in a large-scale manner. In this seminar, we will review and discuss a selection of recently published studies on single-cell technologies and their applications in biology and medicine. Students will get insight into cutting-edge research-relevant material, train their ability to understand and critically assess scientific articles, and practice their presentation skills. Die Veranstaltung vermittelt: 40 % Analyse & Methodik, 30 % Wissen & Verstehen, 30 % Recherche & Bewertung

Content

1) Strategies in single-cell omics for: transcriptional, genome, and epigenetic profiling 2) Applications of single-cell methods in research with a focus on: − Cell type identification in complex tissues − Cancer biology

Module Components

Pflichtgruppe:

All Courses are mandatory.

Course Name	Type	Number	Cycle	Language	SWS	VZ
Single-cell technologies	SEM		SoSe	English	2

Workload and Credit Points

Single-cell technologies (SEM):

Workload description	Multiplier	Hours	Total
Präsenzzeit	1.0	15.0h	15.0h
			15.0h(~1 LP)

Course-independent workload:

Workload description	Multiplier	Hours	Total
Prüfungsvorbereitung	1.0	15.0h	15.0h
Vor- und Nachbereitung des Seminars	15.0	2.0h	30.0h
			45.0h(~2 LP)

The Workload of the module sums up to 60.0 Hours. Therefore the module contains 2 Credits.

Description of Teaching and Learning Methods

A short introduction will be given at the beginning of the course. Relevant scientific publications will be identified to be used as primary literature. Each selected paper will then be presented by a student and discussed in the group. The course will be held in English.

Requirements for participation and examination

Desirable prerequisites for participation in the courses:

Basic understanding of biological concepts Solid fundamentals in genetics, gene regulation, and molecular biology

Mandatory requirements for the module test application:

This module has no requirements.

Module completion

Grading

graded

Type of exam

Oral exam

Language

English

Duration/Extent

30 min

Duration of the Module

The following number of semesters is estimated for taking and completing the module:
1 Semester.

This module may be commenced in the following semesters:
Sommersemester.

Maximum Number of Participants

The maximum capacity of students is 10.

Registration Procedures

Anmeldung erfolgt über ISIS 2

Recommended literature
To be determined at the beginning of the course.

Assigned Degree Programs

This module is not used in any degree program.

Miscellaneous

Modul für den Master-Studiengang Biotechnologie

Single-cell technologies