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WiSe 2020/21 - SoSe 2021


Bioprocess development from high throughput screening to production


Neubauer, Peter


Mündliche Prüfung


Fakultät III

Institut für Biotechnologie

33311200 FG Bioverfahrenstechnik

MSc Biotechnologie


ACK 24

Hans, Sebastian


Learning Outcomes

The students will learn: - have a sound basic knowledge of automated screening, cultivation and process development methods of biotechnologically products - Know the theoretical basis of the individual basic operations and be able to assess their limits, - have an overview of the currently available Liquid Handling Stations and their operation - use model to represent, monitor and control bioprocesses - are able to create small models based on literature and your knowledge - have knowledge of the methods of product development in biotechnological processes The event mainly mediates: 20% knowledge & understanding, 15% analysis & methodology, 15% development & design, 10% research & evaluation, 20% application & practice, 20% social competence


- Lectures and seminars on the topics: - Modelling and simulation of bioprocesses - Modell predictive control - Consistent bioprocess development - Automation in Bioprocess development - Screening and cultivation methods on a micro scale from μl- to ml-scale (microtiter plates, deep well plates, microbioreactors) - Practical exercise: - creating a mechanistic model in python - writing an automation protocol for a liquid handling station (Tecan or Hamilton)

Module Components


All Courses are mandatory.

Course NameTypeNumberCycleLanguageSWSVZ
Bioprocess development from high throughput screening to productionIVWiSeEnglish6

Workload and Credit Points

Bioprocess development from high throughput screening to production (IV):

Workload descriptionMultiplierHoursTotal
Time of presence15.06.0h90.0h
Project work15.06.0h90.0h
Pre-/ postprocessing15.06.0h90.0h
270.0h(~9 LP)
The Workload of the module sums up to 270.0 Hours. Therefore the module contains 9 Credits.

Description of Teaching and Learning Methods

Lectures and seminars as well as preparation based on relevant technical literature. Modelling and automation exercise in working groups of about 2-3 students. Lecture event to present the results. Language of instruction: usually English, unless all participants have German as their mother tongue.

Requirements for participation and examination

Desirable prerequisites for participation in the courses:

Good to very good knowledge of English, and completion of BVT I and BVT II

Mandatory requirements for the module test application:

This module has no requirements.

Module completion



Type of exam

Oral exam




No information

Duration of the Module

The following number of semesters is estimated for taking and completing the module:
1 Semester.

This module may be commenced in the following semesters:

Maximum Number of Participants

The maximum capacity of students is 20.

Registration Procedures

See corresponding notes on the homepage of the Chair of Biochemical Engineering (www.bioprocess.tu-berlin.de). Registration via ISIS.

Recommended reading, Lecture notes

Lecture notes

Availability:  unavailable


Electronical lecture notes

Availability:  available
Additional information:
siehe ISIS2-Kursseite



Recommended literature
Material is provided in electronic form via ISIS or directly via the homepage of the Chair of Biochemical Engineering.
Group specific parts are provided directly in the course.

Assigned Degree Programs

This module is used in the following Degree Programs (new System):

Studiengang / StuPOStuPOsVerwendungenErste VerwendungLetzte Verwendung
This module is not used in any degree program.

Students of other degrees can participate in this module without capacity testing.


Elective module in the Master's programme Biological Chemistry. To ensure the successful completion of the module, a good command of English is recommended.